Her primary appearance was updated as her peaked cap is now dark pink with a gray skull design at the center. In her full appearance in Street Fighter V, Poison finally cuts her long hair into a shoulder-length coif bob in a style of disheveled spikes downward. Her cut-off denim shorts are now black, which also shows her the lines of her red thong beneath her shirt and has a gold band on her right thigh and her red high heels are maintained. She also has white elbow band on her left elbow. In her concept art in Street Fighter V, Poison's outfit has minor changes, her skimpy tank top has been replaced with a bandage styled shirt which has covered in her top and has a single left long sleeve beneath it. Roxy was from the same orphanage that Poison grew up at, according to Capcom Classics Collection, which also mentions that she looks up to Poison. Roxy is identical to Poison, though she has reddish-orange hair instead of purple, and has lower health. There is also a palette-swap of Poison called Roxy. This appearance later became as her 'Nostalgia' costume in Street Fighter V. Since Final Fight Revenge, she usually carries a riding crop that she uses as a weapon. She also has a chain around her waist, a studded black collar on her neck, and a pair of handcuffs hanging from the chain around her waist.

Poison has long pink hair and wears a black peak cap with a chain-link design, a skimpy white midriff-revealing tank top, and a pair of skimpy denim 'Daisy Dukes' cut-off shorts and high heels.

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